Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia.

BACKGROUND: Deregulated miRNA expression plays a crucial role in carcinogenesis.Recent studies show different mechanisms leading to miRNA deregulation in cancer; however, alterations CONSOLE MAST SET affecting miRNAs by DNA copy number variations (CNV) remain poorly studied.RESULTS: Our integrative analysis including data from high resolution SNPs

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Guideline-based bismuth quadruple therapy for helicobacter pylori infection in China: A systematic review and network meta-analysis.

BackgroundCurrently, quadruple therapy is unanimously recommended as the current first-line treatment option for Helicobacter pylori (H.Pylori) eradication.However, the drug composition of quadruple therapy is very complex, and the efficacy and safety between them is not clear.AimsTo compare the efficacy and safety of H.Pylori eradication regimens,

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